Cardiovascular Risk Profile
The Cardiovascular Risk Profile from Doctor’s Data reviews a thorough battery of biomarkers to aid in early detection and reduction of risk factors before the disease progresses.
Total and LDL cholesterol, total triglyceride and HDL cholesterol have traditionally been measured to gauge CVD risk. However, recent research indicates that more focused biomarkers can provide even greater insight.
For example, oxidized LDL is plaque-specific and directly involved in accelerated atherogenesis and late-stage atherosclerotic plaque instability and rupture. Small dense LDL exhibits greater penetration into the arterial wall and has a longer half-life as well as lower resistance to oxidation compared to that of the large buoyant LDL. Circulating levels of these two markers are:
- Strong independent CVD risk factors
- Higher in CVD patients
- Correlated with the severity of CVD
- Not correlated with LDL cholesterol levels
In addition, levels of apolipoproteins A-1 and B, specific protein constituents of HDL and LDL, are also strong indicators of risk.